Sinner earlier continued his perfect start to the season to improve his win-loss record this year to 16-0.

World number one and US Open winner Alcaraz, playing only his fourth grass-court tournament, defeated Daniil Medvedev 6-3, 6-3, 6-3.

Having battled through 59 encounters with Rafael Nadal over 16 years of epic rivalry, Novak Djokovic faces the Spanish legend's heir apparent Carlos Alcaraz at the French Open in a match laced with era-defining potential.

Top seed Daniil Medvedev will open his U.S. Open title defence onMonday against American Stefan Kozlov but faces major hurdles on the path to a second Grand Slam title at Flushing Meadows, including in-form Australian Nick Kyrgios.

Spanish teenage sensation Carlos Alcaraz and third seed Alexander Zverev both saved a match point in five-set French Open thrillers, while 13-time winner Rafael Nadal and reigning champion Novak Djokovic eased into the third round Wednesday.